求翻译帝翻译下一段话Owing to the complementary roles of NEP and APN in

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求翻译帝翻译下一段话
Owing to the complementary roles of NEP and APN in
enkephalin inactivation, selective inhibition of only one of the
two peptidases, such as thiorphan, gives weak antinociceptive
responses even after central administration in rodents [13,14].
In humans, thiorphan was found inactive, even after intravenous
(i.v). or pulmonary administration [15,16]. This led one
to propose the concept of dual inhibitors, that is compounds
able to simultaneously block NEP and APN activities (review
in [7,17]). This was possible owing to the fact that these two
membrane-bound enzymes belong to the superfamily of zinc
metallopeptidases.

由于中性内肽酶(NEP)和心钠肽(ANP)在脑啡肽失活中的相互作用,选择性地抑制这2种肽酶之一,如消旋卡多曲代谢物Thiorphan（TP）,即使啮齿类中枢吸收后,镇痛效果还是减弱.对于人类,即使静脉注射或肺部吸收,TP也不活跃.由此产生一个概念,加倍抑制.那就是能同时阻止NEP和ANP活动的合剂.这可能是基于2种属于锌金属肽酶家族的膜结合酶的事实.

医学翻译最难了,特别对于非医专业的.
以后记得悬赏啊!

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